MLPA. Multiplex Ligation–dependent Probe Amplification

The MLPA is a molecular, economic and effective method for the study of copy number variants.

We use both commercial probes produced by MRC-Holland as well as probes designed by us in case there are no commercial probes available.
Using variants of the MLPA we can also perform studies of methylation sensitive loci, such as the PW / AS syndrome region, among others.